Which statement regarding irritant contact dermatitis (ICD) is NOT correct?

Irritant contact dermatitis (ICD) is indeed characterized by symptoms like dryness, itching, and burning sensations, which makes option B an incorrect statement regarding ICD. The condition arises from direct damage to the skin barrier due to irritants, which can include various substances like soaps, detergents, or hand sanitizers.

The symptoms arise because the skin's protective barrier becomes compromised, leading to inflammation. This results in a range of discomforting sensations, aligning well with the known characteristics of ICD.

In contrast, the other statements accurately describe the nature and implications of irritant contact dermatitis. It is the most common reaction associated with frequent use of hand hygiene products due to the frequent exposure to irritating substances. Furthermore, skin damage from ICD can create an environment that may allow for colonization by bacteria, such as staphylococci and gram-negative bacilli, thus highlighting the importance of understanding and managing irritants to maintain skin health. Finally, it is significant to note that ICD is not immunologically mediated; instead, it results from non-specific irritation rather than an immune response, setting it apart from allergic contact dermatitis, which is indeed immunologically driven.