How do keratinocytes respond to skin trauma?

Keratinocytes play a critical role in the body's response to skin trauma. When the skin experiences injury, these cells respond by increasing their maturation rates. This is part of a broader biological process aimed at repairing the epidermis and restoring the skin barrier. The enhanced maturation of keratinocytes facilitates faster migration to the wound site, promoting re-epithelialization, which is essential for wound healing. This rapid response helps close the wound and prevents potential infections or further damage.

The option indicating decreased proliferation would be inconsistent with the body’s need for rapid repair following trauma, as increased cell division is essential for effective healing. Remaining dormant would not support the healing process, and while keratinocytes can indeed contribute to repairing the epidermis within 24 hours, the increasing maturation rates specifically highlight the mobilization and functionality of keratinocytes during the healing process.